The additional variables identified include but are not limited to those involving signaling dynamics for mitochondria, possible disruptions in processes for apoptosis (cell death), imbalances in surface proteins responsible for apoptosis, and the disruption of homeostatic relationships of other tumor markers currently used as individual biomarkers (e.g. alpha-fetoprotein - AFP). Because linkages between corollary relationships of the various substances associated with the aforementioned processes are not obvious in current literature without considering homeostasis, adequate explanations will require detailed discussions with members of the research community.

Included in discoveries made by The Center, the application of the rate of cellular absorption also appears to be a major factor in breast cancer as well as most other disease entities. This transformational model for cellular absorption expands the maxim of toxicology postulated by Paracelsus (1493 - 1541) from "the dose determines the poison" to include - "the rate of cellular absorption determines the level of toxicity." The model for cellular absorption is explained on The Center's web site in the tab for Life Sciences.

Angelini explained, "Identifying causal paths for any disease state has been elusive because so many disruptions must occur at the same time. Traditional cause and effect modeling has not been able to produce the desired results."

Linda Oliver-Perrier, the spokesperson for The Center's Life Sciences group explained, "Our intention was not to become involved with scientific research methodologies. While finalizing a business model utilizing neuroscience in business for overcoming change inertia, one of our team members identified a novel relationship between brain chemicals. The implications of this discovery forced us to set aside the promotion of our completed model for creating a culture of change acceptability. A separate Life Sciences group was then formed to address the model of corollary relationships of substances in the body. The outcome of these investigations into process beyond neurobiology led to the formulation of the irrefutable model for assessing homeostatic relationships between substances in the body."

SOURCE The Center for Modeling Optimal Outcomes LLC